{"id":882,"date":"2016-02-08T15:04:19","date_gmt":"2016-02-08T15:04:19","guid":{"rendered":"http:\/\/synvec.fr\/?p=882"},"modified":"2019-10-06T16:28:58","modified_gmt":"2019-10-06T16:28:58","slug":"les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage","status":"publish","type":"post","link":"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/","title":{"rendered":"Les statines pour retarder l’apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l’\u00e2ge"},"content":{"rendered":"

La d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l’\u00e2ge (DMLA) est une maladie \u00e9volutive de la macula \u00e0 d\u00e9clenchement tardif qui affecte la vision centrale. Des \u00e9tudes ont montr\u00e9 que certains des facteurs pouvant conduire \u00e0 l’ath\u00e9roscl\u00e9rose et aux accidents vasculaires c\u00e9r\u00e9braux sont les m\u00eames que ceux pouvant conduire \u00e0 la DMLA. Les statines se sont av\u00e9r\u00e9es tr\u00e8s efficaces dans la pr\u00e9vention des accidents vasculaires c\u00e9r\u00e9braux, de sorte qu’il est possible qu’elles puissent aussi prot\u00e9ger de la DMLA. Un certain nombre d’\u00e9tudes observationnelles avaient examin\u00e9 la relation entre la DMLA et l’utilisation de statines, mais les r\u00e9sultats \u00e9taient contradictoires.<\/p>\n

Cette revue syst\u00e9matique a identifi\u00e9 un essai contr\u00f4l\u00e9 randomis\u00e9 achev\u00e9 et un en cours. Pour ce qui concerne l’essai achev\u00e9, dans lequel 30 patients avaient re\u00e7u quotidiennement pendant trois mois soit 20 mg de simvastatine soit un placebo, les analyses n’ont pas montr\u00e9 de diff\u00e9rence statistiquement significative dans l’acuit\u00e9 visuelle \u00e0 la fin du traitement ou 45 jours apr\u00e8s l’ach\u00e8vement du traitement. Pour l’essai en cours, les analyses pr\u00e9liminaires apr\u00e8s 12 mois de traitement n’ont pas montr\u00e9 de diff\u00e9rence statistiquement significative entre 40 mg quotidiens de simvastatine et un placebo, au niveau de l’acuit\u00e9 visuelle, de l’accumulation des drusens ou de la fonction visuelle. Vues la petite taille de l’essai termin\u00e9 et la courte dur\u00e9e du traitement et de la p\u00e9riode de suivi, aucune conclusion concernant les effets des statines sur l’apparition ou la progression de la DMLA ne peut \u00eatre tir\u00e9e \u00e0 ce jour. Nous mettrons \u00e0 jour cette revue lorsque les donn\u00e9es de l’essai en cours seront disponibles.<\/p>\n

Souce link :\u00a0http:\/\/www.cochrane.org\/fr\/CD006927\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage<\/p>","protected":false},"excerpt":{"rendered":"

La d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l’\u00e2ge (DMLA) est une maladie \u00e9volutive de la macula \u00e0 d\u00e9clenchement tardif qui affecte la vision centrale. Des \u00e9tudes ont montr\u00e9 que certains des facteurs pouvant conduire \u00e0 l’ath\u00e9roscl\u00e9rose et aux accidents vasculaires c\u00e9r\u00e9braux sont…<\/p>\n","protected":false},"author":1,"featured_media":883,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"yoast_head":"\nLes statines pour retarder l'apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l'\u00e2ge - SYNVEC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les statines pour retarder l'apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l'\u00e2ge - SYNVEC\" \/>\n<meta property=\"og:description\" content=\"La d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l’\u00e2ge (DMLA) est une maladie \u00e9volutive de la macula \u00e0 d\u00e9clenchement tardif qui affecte la vision centrale. Des \u00e9tudes ont montr\u00e9 que certains des facteurs pouvant conduire \u00e0 l’ath\u00e9roscl\u00e9rose et aux accidents vasculaires c\u00e9r\u00e9braux sont...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/\" \/>\n<meta property=\"og:site_name\" content=\"SYNVEC\" \/>\n<meta property=\"article:published_time\" content=\"2016-02-08T15:04:19+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-10-06T16:28:58+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/synvec.fr\/wp-content\/uploads\/2016\/02\/Sans-titre.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"662\" \/>\n\t<meta property=\"og:image:height\" content=\"366\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/\",\"url\":\"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/\",\"name\":\"Les statines pour retarder l'apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l'\u00e2ge - SYNVEC\",\"isPartOf\":{\"@id\":\"https:\/\/synvec.fr\/en\/#website\"},\"datePublished\":\"2016-02-08T15:04:19+00:00\",\"dateModified\":\"2019-10-06T16:28:58+00:00\",\"author\":{\"@id\":\"https:\/\/synvec.fr\/en\/#\/schema\/person\/7b52bb16f00f76d7dae548863f6fbb31\"},\"breadcrumb\":{\"@id\":\"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/synvec.fr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Les statines pour retarder l’apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l’\u00e2ge\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/synvec.fr\/en\/#website\",\"url\":\"https:\/\/synvec.fr\/en\/\",\"name\":\"SYNVEC\",\"description\":\"Votre Partenaire en R&D et Synth\u00e8se Chimique\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/synvec.fr\/en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/synvec.fr\/en\/#\/schema\/person\/7b52bb16f00f76d7dae548863f6fbb31\",\"name\":\"admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/synvec.fr\/en\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/9472d6ba1967673e72cbcbfc3777bbed?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/9472d6ba1967673e72cbcbfc3777bbed?s=96&d=mm&r=g\",\"caption\":\"admin\"},\"url\":\"https:\/\/synvec.fr\/en\/author\/admin\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Les statines pour retarder l'apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l'\u00e2ge - SYNVEC","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/","og_locale":"en_US","og_type":"article","og_title":"Les statines pour retarder l'apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l'\u00e2ge - SYNVEC","og_description":"La d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l’\u00e2ge (DMLA) est une maladie \u00e9volutive de la macula \u00e0 d\u00e9clenchement tardif qui affecte la vision centrale. Des \u00e9tudes ont montr\u00e9 que certains des facteurs pouvant conduire \u00e0 l’ath\u00e9roscl\u00e9rose et aux accidents vasculaires c\u00e9r\u00e9braux sont...","og_url":"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/","og_site_name":"SYNVEC","article_published_time":"2016-02-08T15:04:19+00:00","article_modified_time":"2019-10-06T16:28:58+00:00","og_image":[{"width":662,"height":366,"url":"https:\/\/synvec.fr\/wp-content\/uploads\/2016\/02\/Sans-titre.jpg","type":"image\/jpeg"}],"author":"admin","twitter_card":"summary_large_image","twitter_misc":{"Written by":"admin","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/","url":"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/","name":"Les statines pour retarder l'apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l'\u00e2ge - SYNVEC","isPartOf":{"@id":"https:\/\/synvec.fr\/en\/#website"},"datePublished":"2016-02-08T15:04:19+00:00","dateModified":"2019-10-06T16:28:58+00:00","author":{"@id":"https:\/\/synvec.fr\/en\/#\/schema\/person\/7b52bb16f00f76d7dae548863f6fbb31"},"breadcrumb":{"@id":"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/synvec.fr\/en\/les-statines-pour-retarder-lapparition-et-la-progression-de-la-degenerescence-maculaire-liee-a-lage\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/synvec.fr\/"},{"@type":"ListItem","position":2,"name":"Les statines pour retarder l’apparition et la progression de la d\u00e9g\u00e9n\u00e9rescence maculaire li\u00e9e \u00e0 l’\u00e2ge"}]},{"@type":"WebSite","@id":"https:\/\/synvec.fr\/en\/#website","url":"https:\/\/synvec.fr\/en\/","name":"SYNVEC","description":"Votre Partenaire en R&D et Synth\u00e8se Chimique","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/synvec.fr\/en\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/synvec.fr\/en\/#\/schema\/person\/7b52bb16f00f76d7dae548863f6fbb31","name":"admin","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/synvec.fr\/en\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/9472d6ba1967673e72cbcbfc3777bbed?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/9472d6ba1967673e72cbcbfc3777bbed?s=96&d=mm&r=g","caption":"admin"},"url":"https:\/\/synvec.fr\/en\/author\/admin\/"}]}},"_links":{"self":[{"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/posts\/882"}],"collection":[{"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/comments?post=882"}],"version-history":[{"count":1,"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/posts\/882\/revisions"}],"predecessor-version":[{"id":884,"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/posts\/882\/revisions\/884"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/media\/883"}],"wp:attachment":[{"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/media?parent=882"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/categories?post=882"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/synvec.fr\/en\/wp-json\/wp\/v2\/tags?post=882"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}